Guided Bone Regeneration (GBR) is a well documented and successful technique used by dental surgeons to correct bone deficiencies of the mouth. GBR involves using a membrane to separate a bony defect from overlying soft tissues in order to create an unrestrained space in which new bone growth can occur.

Epi-Guide® Bioresorbable Barrier Matrix is a membrane that has been designed for use in periodontal restorative surgeries to assist in the regeneration of bone and periodontal support tissues. It is a porous, three-dimensional matrix fabricated from D, D-L, L-polylactic acid, a bioresorbable polymer with a long history of safe medical use. The barrier's three-layer construction is designed to attract, trap and retain fibroblasts and epithelial cells while maintaining space around a bony defect for the development of bone and periodontal support tissues. The Epi-Guide® matrix functions as an effective barrier for up to 20 weeks with complete bioresorption occurring between 6-12 months.

The Epi-Guide® barrier is a hydrophilic membrane that quickly absorbs fluid blood and supports healthy clot formation, which is extremely important in maintaining gingival flap viability and coverage - an essential condition needed to prevent bacterial infection associated with barrier exposure. Should the barrier become exposed or if primary closure is not obtained, clotted blood within the barrier provides a natural matrix that allows tissue to quickly grow and cover most exposures. Unlike several other periodontal barriers, the Epi-Guide® matrix is self-supporting and can be used in many situations without support from bone grafting materials.