Meso BioMatrix™ Scaffold for Soft Tissue Repair

The Meso Biomatrix™ Scaffold is a porcine mesothelial extracellular matrix (ECM) product developed for soft tissue repair applications that require enhanced drape and conformability.  It is made from our proprietary OPTRIX™ process, which gently disinfects tissues, inactivates viruses and removes cells while preserving extracellular matrix components.

 

Meso Biomatrix™ Features and Benefits 

Proven In-Vitro biologic activity

Kensey Nash invests in comprehensive analysis of our extracellular matrices to validate the gentle selectivity of the OPTRIX™ process.  In vitro animal studies demonstrate the potential for increased biologic activity:

• More rapid cell infiltration compared to dermis xenograft products ²
• Greater retention of TGF-B and VEGF relative to incumbent commercial products²
• Stimulated human dermal fibroblasts to produce more VEGF than incumbent commercial products²

Potential Clinical Applications

At Kensey Nash we know that every clinical need poses unique challenges and requires specialized tools.  The versatility of our OPTRIX™ processing methods provides the opportunity to address a variety of soft tissue repair needs, such as:

Abdominal Wall Reconstruction  Suture/Staple Line Reinforcement  Plastic and Reconstructive Surgery Pelvic Floor Reconstruction

Dura Substitute  Rotator Cuff Repair  Nerve Conduit

References

1. Kensey Nash, Data on File
2. BioMaterials. 2010 Sep;31(27):6934-40.

Regulatory approvals are necessary before the use of Meso BioMatrix™ in human applications. In vitro data may not be indicative of clinical results.  Meso BioMatrix and OPTRIX are trademarks of Kensey Nash Corporation.